What impact does Neo-Darwinism have on Christianity?

What are the philosophical ramifications of Neo-Darwinism?

Biblical genesis plays a considerable role in defining Christian philosophical concepts; for example: what does it mean to be human? What is sin? Darwinism overwrites all of this. 

I only ever see people talking about the science of Darwinism, never really about the philosophical ramifications. So, my question is: What are the philosophical ramifications of Neo-Darwinism?

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I recommend that you look at Mapping the Origins Debate by Gerald Rau. He identifies six worldviews and explores how each of them deals with the data. Perhaps that will give you a more comprehensive answer to your question.

In short, the Neo-Darwinian account contradicts two of the four worldviews open to Christians. If common descent is true, then creationism is false. If someone could demonstrate the truth of Neo-Darwinism, then the Christian would have to endorse either planned evolution or directed evolution.

Planned evolution is the view that God intended the evolutionary process when he created the universe. His creative act at the beginning was specific enough to set in motion the chain of events that would eventually lead to the diversity we see today on planet earth.

Directed evolution holds that God intervened at specific points to drive the evolutionary process forward at those stages when the naturalistic mechanisms were insufficient.